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CDC warns about 'rhino tranq,' a mix of fentanyl and animal sedative that resists overdose reversal

April 4, 2026

Fentanyl alone is dangerous enough, but now comes a warning about “rhino tranq,” which is fentanyl laced with the animal sedative medetomidine, making it even more lethal. Adding to the danger, it doesn’t respond to overdose reversal medications.

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